The best advice, given by Neil Gaiman in a graduation speech at the University of the Arts in Philadelphia, and illustrated by Gavin Aung Than. I encourage clicking through to see the rest of this comic on zenpencils (it's funny - you'll like it!) and viewing the commencement address on vimeo.
You know that making good scarves was instrumental to my recovery when things got tough last year. And now I find that making things - art or craft, good or bad - is always a great tool to lift my mood and help me center, no matter what the problem.
The other secret weapon against tough times is to do something nice or helpful for someone else. Bonus if you can make good art for someone else.